Methylation Silencing of the Apaf-1 Gene in Acute Leukemia
نویسندگان
چکیده
منابع مشابه
Aberrant Methylation of APAF-1 Gene in Acute Myeloid Leukemia Patients
Background: Acute myeloid leukemia (AML) is a heterogeneous clonal disorder characterized by immature myeloid cell proliferation and bone marrow failure. Various genetic and epigenetic factors have been found to be influential in such patients. Methylation silencing of APAF-1, a putative tumor suppressor gene (TSG), has been found in several human malignancies. In this study, we explored the as...
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ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2005
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-04-0105